Questions & Answers

Everygene, PBC makes hospital-grade genetic testing affordable and accessible. Our mission is to prevent anyone from dying from a genetic condition that early testing could have caught.

Everygene samples are processed at Broad Clinical Labs, and our tests are developed in collaboration with Mass General Brigham, two of the most trusted names in genomics and medicine.

Broad Clinical Labs is CLIA certified, and every result is reviewed by a board-certified clinical geneticist.

If we find a positive result, we run your sample a second time using another method to confirm it before releasing your report. This is the same process used in top academic hospitals, and it is built into every Everygene test.

We’re 100% focused on health. Unlike other companies that offer entertainment, ancestry, or wellness insights, Everygene is dedicated to the early detection of serious, but treatable, genetic conditions.

Our goal is simple: help people uncover hidden health risks before symptoms appear, when they can still be prevented or managed.

The Everygene Health Screen is a one-time genetic test that looks at 84 medically actionable genes identified by the American College of Medical Genetics and Genomics (ACMG). These genes are linked to serious, but treatable, conditions such as heart disease and cancer.

This test is for anyone who wants to understand their genetic risk before symptoms appear. It may be especially helpful if you:

• Have a family history of cancer or heart disease
  Certain genes such as BRCA1 and BRCA2 can increase your risk of breast, ovarian, prostate, and other cancers. Others are linked to heart conditions like Long QT syndrome or cardiomyopathy that may not show up until later in life.
  
• Are an athlete or do intense physical activity
  Some heart-related genetic conditions only become dangerous during physical stress. This test can help identify those risks early.
  
• Are planning to have children
  Some of the genes in this screen can be passed down even if you do not have symptoms yourself. Knowing your status can help you plan ahead.
  
• Just want to be proactive about your health
  Many people carry actionable genetic risks without knowing it. This test helps find them early, when they can still be treated or managed.

Roughly 3% of people—about 10 million Americans—carry genetic variants linked to preventable conditions. Finding these risks early gives you and your healthcare provider the opportunity to act before symptoms start.

We do not share your personally identifiable data with third parties. Unlike some other companies, we also do not sell or share your de-identified data without your permission.

In the future, we plan to build features that let you choose if and how to share your data. These features will always be opt-in, never the default.

This test is for patients who have been diagnosed with non-ischemic or idiopathic cardiomyopathy.

Yes. If your previous testing was inconclusive or identified a genetic cause, you may still qualify and benefit from additional testing.

Yes. If a family member has tested positive for a genetic cardiomyopathy, you can get a genetic test for $349.

Everygene will never share your personally identifiable information with third parties.

Everygene de-identifies and aggregates any health data that can be used specifically to treat or cure genetic cardiomyopathy and "throws away the key" so it cannot be re-identified. We may share this de-identified and aggregated data with researchers to accelerate scientific progress specifically toward finding a cure for genetic cardiomyopathy.

Genetic and clinical health data, once combined and analyzed, help researchers better understand the underlying causes of genetic cardiomyopathy. This accelerates the discovery of new medications and treatments, bringing effective therapies to patients sooner.

Results are typically available 4-8 weeks after we receive your sample.

Once your results are ready, we will send you an email and a message in your patient portal.

For anyone who tests positive, we offer a free, 30-minute genetic counseling session with a licensed genetic counselor. Every person who gets tested also receives results from Mass General Brigham and an easy-to-read action plan, all in your patient portal under "My Results".

Please email us anytime at support@everygene.com. Also, for positive results, there is a chat function available under the "Results" tab in your patient portal to ask your assigned genetic counselor questions for up to 60 days after you receive your results.

Sequencing is the process of reading the complete or partial DNA code from your sample. Testing involves analyzing that DNA information to look for specific changes or variants that may impact your health.

Your DNA is sequenced at Broad Clinical Labs, the largest sequencing lab in the U.S.

Your genetic test is done at the Laboratory of Molecular Medicine at Mass General Brigham.

We give you access to your full genome data file (a downloadable .vcf) so you can use it however you choose, including with other tools or services now or in the future.

Your genetic code does not change, and as science advances, your data will continue to be valuable for years to come.

Adults (18+) with a diagnosis of idiopathic or non-ischemic cardiomyopathy, consistent with current AHA/ACC/HFSA and ESC guidelines. Free testing is for probands only. Cascade testing for relatives is available at reduced cost once a pathogenic or likely pathogenic variant is identified.

Two options:

1. Order kits for your office — keep them on hand and distribute to eligible patients.
2. Refer patients directly to Everygene.com — patients can request a kit, register, and consent on their own.

All patients must register their kit online before testing can begin.

Yes. Kits can be shipped to any U.S. address except in the state of New York. You can request a supply for your practice or have patients request one themselves.

Patients register the kit online, complete eligibility and consent, provide a cheek swab (no food/drink/gum 30 minutes prior), and return it using prepaid mail.

Everygene works with Broad Clinical Labs for sequencing (blended genome-exome).

Everygene works with Mass General Brigham’s Laboratory for Molecular Medicine (LMM) for expert cardiomyopathy-specific interpretation and reporting.

Typically 4–6 weeks after the lab receives the sample. Patients receive email updates at key steps.

For Positive results (pathogenic or likely pathogenic):
Patients receive notification in the Everygene portal to schedule a visit with a genetic counselor. They receive the results during their genetic counseling session. DNAvisit verifies the patient’s ordering provider and faxes results to your office. Patients are also encouraged to upload results via MyChart or bring a copy.

For Negative results:
Patients receive notification in the Everygene portal. Providers are not sent separate reports for negatives. If you would like results delivered in a different way, please email support@everygene.com to clarify your preferred method.

Pathogenic and likely pathogenic variants. Variants of uncertain significance (VUS) are not included. If positive, patients also receive a genetic counseling summary letter.

Our standard reporting policy is to return only actionable variants. However, in rare situations — such as when a provider observes a strong family trend — we are open to case-by-case discussions regarding VUS results.

Yes. Patients with a positive result are offered free, virtual counseling through DNAvisit. Counseling includes explanation of results, care and family implications, and support for next steps.

Patients may receive a genetic report, a counseling summary (if positive), and guideline-based recommendations for follow-up or family screening.

Yes. Everygene and our partners follow HIPAA regulations and industry best practices to protect patient privacy. All genetic and health information is stored securely and transmitted through encrypted, compliant systems.

You can reach us directly at support@everygene.com or by calling 914-391-0535. For urgent clinical questions, please include “Provider Inquiry” in your subject line so we can prioritize your request.